Vascular density in melanoma xenografts correlates with vascular permeability factor expression but not with metastatic potential
نویسندگان
چکیده
منابع مشابه
Analysis of the tumor vasculature and metastatic behavior of xenografts of human melanoma cell lines transfected with vascular permeability factor.
Vascular permeability factor (VPF) is an important mediator of vascular development in tumors. Some human melanoma cell lines have a low VPF expression level in culture, but this level is upregulated when growing as a tumor in nude mice. Other melanoma lines have a constitutively high VPF expression. To compare the biological behavior of tumors with these two expression patterns, a human melano...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1997
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1997.427